The incidence of osteoporosis and associated fractures is found to be lower in countries where the Mediterranean diet is predominant. These observations might be mediated by the active constituents of olive oil and especially phenolic compounds.
The intake of olive oil has been related to the prevention of osteoporosis in experimental and in in vitro models. Very few prospective studies have evaluated the effects of olive oil intake on circulating osteocalcin (OC) in humans.
The objective of the study led by Spanish researchers was to examine the longitudinal effects of a low-fat control diet (n = 34), a Mediterranean diet enriched with nuts (MedDiet+nuts, n = 51), or a Mediterranean diet enriched with virgin olive oil (MedDiet+VOO, n = 42) on circulating forms of OC and bone formation markers in elderly men at high cardiovascular risk.
Consumption of a Mediterranean diet enriched with virgin olive oil for 2 years is associated with increased serum osteocalcin and P1NP concentrations, suggesting protective effects on bone.
Age-related bone mass loss and decreased bone strength is an almost invariable feature of human biology, affecting women and men alike as an important determinant of osteoporosis and fracture risk.
Nutritional factors are known to be involved in age-related bone loss associated with osteoblast insufficiency during continuous bone remodeling, in interaction with a combination of genetic, metabolic, and hormonal factors.How extra virgin olive oil can help our bones?,