EVOO quality is the secret in the prevention of bladder cancer

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The extra virgin olive oil polyphenols suppress the invasive capacity of bladder cancer cells through the modulation of matrix metalloproteinases. Only an extra virgin of high quality, local produced and stored with care preservse maximum biological characteristics and the potential nutraceutical effects.

From the italian olive cultivar Itrana the secret to the prevention of bladder cancer. Fundamental, however, the link with the territory and quality raw material to preserve biological characteristics and potential nutraceutical effects.

The study was published in the journal Nutrition and Cancer.

The research was conducted by the Department of Biotechnology and Medical-Surgical of University La Sapienza- Rome, with the contribution from the Italian League the Fight against Cancer (LILT), the Department of Industry of the Province of Latina.

The extra virgin olive oil is made for 95-99% of triglycerides, rich in unsaturated fatty acids, and for a fraction of 0.4 to 5%, said unsaponifiable rich in polyphenolic compounds.

Epidemiological data indicate that regular consumption of extra virgin was associated with a lower occurrence of cancer, including cancer of the bladder, suggesting the potential protective role of the polyphenolic fraction that is concentrated in the urine. Moreover, several studies have shown that phenolic extracts coming from the leaves or from olives, possess the ability to inhibit the growth of several human tumor cell lines.

One of the main causes of death of bladder cancer is the formation of metastases.

“In the study published in Nutrition and Cancer – says Professor Lendaro, Department of Biotechnology and Medical-Surgical of University La Sapienza- Rome – we focused our attention on the anti-migratory and anti-invasive properties of the polyphenolic fraction extracted from extra virgin olive oil, produced in the province of Latina from Olea europea L. cultivars var. Itrana. The cell models used to demonstrate the potential of this mixture are the two cell lines of human bladder carcinoma particularly “aggressive”.

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